Successful treatment with interferon alfa in infiltrating angiolipoma: a case presenting with Kasabach-Merritt syndrome.

A new successful combination therapy with atenolol and prednisolone for Kasabach-Merritt syndrome

Kasabach-merritt syndrome is a rare life-threatening syndrome associated with vascular tumors such as tufted angioma and kaposiform hemangioendothelioma. For this syndrome, there exist a few treatment modalities with variable results. For many years, corticosteroids have been employed in the first-line therapy. Nowadays, on the other hand, β blockers such as propranolol have been used owing to ...

Paravertebral and Retroperitoneal Vascular Tumour Presenting with Kasabach-Merritt Phenomenon in Childhood, Diagnosed with Magnetic Resonance Imaging

Kasabach-Merritt phenomenon (KMP) is characterized by vascular tumour and consumptive coagulopathy with life-threatening thrombocytopenia, prolonged prothrombin time and partial thromboplastin time, hypofibrinogenemia, and the presence of high fibrin split products. We report a case of 3-year-old boy with local aggressive vascular lesions associated with KMP. Magnetic resonance imaging revealed...

Kaposiform Hemangioendothelioma in a Newborn with Kasabach-Merritt Syndrome

Giant Hepatic Hemangioma With Kasabach–Merritt Syndrome: Is the Appropriate Treatment Enucleation or Liver Transplantation?

We present a case of giant cavernous hemangioma of the liver with disseminated intravascular coagulopathy (Kasabach-Merritt syndrome) which was cured by enucleation. The 51 year old woman presented with increased abdominal girth and easy bruisability. Workup elsewhere revealed a massive hepatic hemangioma and she was started on radiation therapy to the lesion and offered an orthotopic liver tra...

Excellent outcome of medical treatment for Kasabach-Merritt syndrome: a single-center experience

BACKGROUND Kasabach-Merritt syndrome (KMS) is a rare but life-threatening illness. The purpose of this study is to report our single-center experience with KMS. METHODS We reviewed the medical records of 13 patients who were diagnosed with KMS between 1997 and 2012 at Samsung Medical Center. Treatment response was defined as follows: 1) hematologic complete response (HCR) - platelet count >13...